Rabbit Anti-LPA1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:LPA1
IR:Immunogen Range:281-364/364
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1902
Swiss Prot:Q92633
Source:KLH conjugated synthetic peptide derived from human EDG2/LPA1:281-364/364
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:EDG2 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. There are eight known members of the EDG receptor family and they are implicated in mediating growth-related effects such as induction of cellular proliferation, alterations in differentiation and survival, and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several proteins not used within 12 hours. Edg2 has been reported in most human tissues, and is especially abundant in brain cortical regions. ESTs have been isolated from bone, brain, breast, connective tissue, embryo, heart/melanocyte/uterus, lung, prostate and uterus libraries.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:2000-5000)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Cow
Horse
Sheep
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： LPA1;EDG 2;hatidic Acid G Prote;G10 protein homolog;GPCR26;Gpcr91;Kdt2;LPAR1_HUMAN;
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