Rabbit Anti-ACAN Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:ACAN
IR:Immunogen Range:2321-2530/2530
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:176
Swiss Prot:P16112
Source:Recombinant human ACAN protein:2321-2530/2530
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Aggrecan is a member of a family of large, aggregating proteoglycans (also including versican, brevican and neurocan) which is found in articular cartilage. Aggrecan is composed of three major domains: G1, G2, and G3. Between the G1 and G2 domains there is an interglobulin region (IGD). The IGD region is the major site of cleavage by specific proteases like metalloproteinases (MMPs) and aggrecanase. Aggrecan cleavage has been associated with a number of degenerative diseases including rheumatoid arthritis and osteoarthritis. There is evidence that this family of proteoglycans modulates cell adhesion, migration, and axonal outgrowth in the CNS.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： ACAN;Aggrecan;Aggrecan core protei;Cartilage-specific p;CSPCP;CSPG1;MSK16;PGCA_HUMAN;
上海滬震實業(yè)有限公司是一家集研發(fā)、生產(chǎn)和銷售于一體的生命科學(xué)實驗室產(chǎn)品生物科技企業(yè)。主營產(chǎn)品：試劑盒，ELISA試劑盒，抗體，重組蛋白，血清，胎牛血清，細胞，原代細胞 細胞培養(yǎng)試劑，常用生化試劑。