Rabbit Anti-ATG1/ULK1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:ATG1/ULK1
IR:Immunogen Range:951-1050/1050
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:8408
Swiss Prot:O75385
Source:KLH conjugated synthetic peptide derived from human ATG1/ULK1:951-1050/1050
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:ULK1 belongs to the serine/threonine protein kinase family. It is involved in axon growth and plays an essential role in neurite branching during sensory axon outgrowth. Knockdown of ULK1 results in impaired endocytosis of nerve growth factor (NGF), excessive axon arborization, and severely stunted axon elongation indicating that ULK1 mediates a non clathrin coated endocytosis in sensory growth cones. Knockdown of ULK1 also inhibits the autophagic response. It appears to act as a convergence point for multiple signals that regulate autophagy, and in turn interacts with a large number of autophagy related (Atg) proteins.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(0.5μg /Test)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Pig
Cow
Horse
Rabbit
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： ATG1/ULK1;ATG 1;ULK1;ATG1;ATG1A;Serine/threonine pro;Unc 51 like kinase 1;ULK1_HUMAN;
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