Rabbit Anti-CIDEB Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:CIDEB
IR:Immunogen Range:118-219/219
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:27141
Swiss Prot:Q546V8
Source:KLH conjugated synthetic peptide derived from human CIDEB:118-219/219
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as an inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE A and CIDE B were recently identified. CIDE contains a new type of domain termed CIDE N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE B induces apoptosis, which is inhibited by DFF45. CIDE B is a DFF45 inhibitable effector that promotes cell death and DNA fragmentation. CIDE B is expressed mainly in liver and small intestine and at lower levels in spleen, colon, kidney, peripheral blood lymphocytes, and bone marrow.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： CIDEB;cell death activator; Cell death activato;Cell death inducing ;CIDEB_HUMAN;1;cell death-inducing ;Cide-b;
上海滬震實業(yè)有限公司是一家集研發(fā)、生產和銷售于一體的生命科學實驗室產品生物科技企業(yè)。主營產品：試劑盒，ELISA試劑盒，抗體，重組蛋白，血清，胎牛血清，細胞，原代細胞 細胞培養(yǎng)試劑，常用生化試劑。