Rabbit Anti-TRAF3 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:TRAF3
IR:Immunogen Range:101-200/568
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:7187
Swiss Prot:Q13114
Source:KLH conjugated synthetic peptide derived from human TRAF3:101-200/568
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1μg/Test)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： TRAF3;CAP 1;CAP1;D40 associated prote;CD40 binding protein;CD40 bp;CD40 receptor associ;TRAF3_HUMAN;
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