Rabbit Anti-CTH Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:CTH
IR:Immunogen Range:51-150/405
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1491
Swiss Prot:P32929
Source:KLH conjugated synthetic peptide derived from human CTH/CSE/Cystathionase:51-150/405
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Catalyzes the last step in the transsulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure.
Defects in CTH are the cause of cystathioninuria (CSTNU). It is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine, leading to increased urinary excretion.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-F(1:100-500)
Flow-Cyt(2ug/Test)
IF(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
Dog
Cow
Rabbit
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： CTH;CGL_HUMAN;CTH;Cystathionine gamma ;MGC9471;CSE;Cystathionase;Cysteine desulfhydra;
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