Rabbit Anti-Axin1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Axin1
IR:Immunogen Range:761-862/862
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:8312
Swiss Prot:O15169
Source:KLH conjugated synthetic peptide derived from human Axin1:761-862/862
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin (cadherin-associated protein), beta 1, 88kDa, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Sheep
Guinea Pig
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： Axin1;AI316800;AXIN1_HUMAN;Axis inhibition prot;Axis Inhibitor 1;Fu;fused;MGC132911;
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