Rabbit Anti-PLAUR Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:PLAUR
IR:Immunogen Range:201-300/335
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:5329
Swiss Prot:Q03405
Source:KLH conjugated synthetic peptide derived from human PLAUR:201-300/335
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol(GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Cow
Sheep
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： PLAUR;Plasminogen activato;Monocyte activation ;U-PAR;UPAR;MO3;CD87;URKR;
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