Rabbit Anti-PAX8 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:PAX8
IR:Immunogen Range:21-130/457
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:7849
Swiss Prot:Q06710
Source:KLH conjugated synthetic peptide derived from human PAX8:21-130/457
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This protein is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain, an octapeptide, and a paired-type homeodomain. This family plays critical roles during fetal development and cancer growth. The specific function of the PAX8 is unknown but it may involve kidney cell differentiation, thyroid development, or thyroid dysgenesis. Alternative splicing in the gene by inclusion or exclusion of exons 7 and/or 8 has produced several known products but the biological significance of the variants is unknown. Several other splice variants have been proposed but the full nature of these products has not been described. Pax8 is also a marker of otic progenitor cells.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1μg/Test)
ICC(1:100)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Cow
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： PAX8;Paired Box Gene 8;paired ;homeotic ;gene 8;Paired box protein P;PAX 8;PAX8_HUMAN;
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