Rabbit Anti-KISS1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:KISS1
IR:Immunogen Range:81-145/145
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:3814
Swiss Prot:Q15726
Source:KLH conjugated synthetic peptide derived from human Kiss-1:81-145/145
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. [provided by RefSeq, Mar 2012]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Cow
Sheep
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： KISS1;KISS1_HUMAN;Metastasis-suppresso;Kisspeptin-1;Metastin;Kisspeptin-54;Kisspeptin-14;Kisspeptin-13;
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