Product Name：Alloferon
CAS No.：347884-61-1
Synonyms：Alloferon 1；Antimicrobial peptide；麗蠅抗病毒肽1
Catalog No.：218P378
Brand：HongTide（上海鴻肽生物）
Description：Alloferon是一類從細菌感染的果蠅分離得到的十三肽，具有抗腫瘤、抗病毒、抗炎癥、免疫調(diào)控的多重生物活性，其發(fā)揮作用的機理類似免疫調(diào)節(jié)肽，通過激發(fā)機體自然殺傷細胞NK的細胞毒殺作用及促進干擾素INF-α來發(fā)揮其生物活性。2003年，Alloferon成功在俄羅斯上市，臨床適應癥為女性人乳頭瘤病毒HPV感染。鑒于Alloferon的獨特優(yōu)勢，如無細胞毒性、無免疫原性、無突變或致癌效應、無胚胎毒性、無生殖毒性，對于其衍生物的研究將為創(chuàng)造出更高效、安全的抗菌肽AMP、抗腫瘤多肽ACP。
Alloferon is a kind of thirteen peptides isolated from bacterial infected Drosophila melanogaster, which has multiple biological activities of anti-tumor, anti-virus, anti-inflammatory, and immune regulation. Its mechanism of action is similar to that of immune regulatory peptides. It can stimulate the cytotoxicity of Natural killer cell NK and promote interferon INF- α To exert its biological activity. In 2003, Alloferon was successfully launched in Russia, with a clinical indication of female human papillomavirus HPV infection. In view of the unique advantages of Alloferon, such as no cytotoxicity, no immunogenicity, no mutation or carcinogenic effect, no embryotoxicity, no Reproductive toxicity, the research on its derivatives will create more efficient and safe Cathelicidin AMP and anti-tumor polypeptide ACP.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | HGVSGHGQHGVHG |
Sequence(3-letter code) | H-His-Gly-Val-Ser-Gly-His-Gly-Gln-His-Gly-Val-His-Gly-OH |
Peptide Structure |  |
Molecular Formula | C52H76N22O16 |
Molecular Weight | 1265.32 |
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關(guān)鍵字： 347884-61-1;Alloferon;麗蠅抗病毒肽1;多肽;多肽合成;
上海鴻肽生物科技有限公司（簡稱：鴻肽生物）是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務科技公司。公司現(xiàn)有產(chǎn)品涵蓋：定制多肽、目錄多肽、氨基酸衍生物、小分子化合物；公司自成立以來，秉持“用質(zhì)量作船， 以服務為帆，為科研服務”的企業(yè)理念，為國內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務及產(chǎn)品。