Product Name：[Pyr3]-Amyloid β-Protein (3-42)
CAS No.：183449-57-2
Synonyms：淀粉樣蛋白[Pyr3]-Amyloid β-Protein (3-42)
Catalog No.：107P96
Brand：HongTide（上海鴻肽生物）
Description：[Pyr3]-Amyloid β-Protein (3-42)是β淀粉樣肽的改造序列，選取序列中第3-42個(gè)氨基酸，序列中第1個(gè)氨基酸由Glu換成Pyr。發(fā)現(xiàn) (Pyr3)-淀粉樣蛋白 β-蛋白 (3-42) 是沉積在阿爾茨海默病和唐氏綜合癥患者大腦中的主要淀粉樣蛋白 β-肽結(jié)構(gòu)。 因此，建議 (Pyr3)-Aβ (3-42) 在大腦中積累并觸發(fā)不溶性淀粉樣蛋白 β-肽沉積物的形成。 [Pyr3]-Amyloid β-Protein (3-42)可用于研究截短的 Aβ 序列的朊病毒樣行為和 tau 依賴性細(xì)胞毒性。
[Pyr3] - Amyloid β- Protein (3-42) is β The modified sequence of amyloid peptide was selected, with the 3rd to 42nd amino acids in the sequence, and the first amino acid in the sequence was replaced by Pyr instead of Glu. Discovery (Pyr 3)- Amyloid protein β- Protein (3-42) is the main amyloid protein deposited in the brain of patients with Alzheimer's disease and Down syndrome β- Peptide structure. Therefore, it is recommended that (Pyr 3)- A β (3-42) Accumulation and triggering of insoluble amyloid protein in the brain β- The formation of peptide deposits. [Pyr3] - Amyloid β- Protein (3-42) can be used to study truncated A β Prion like behavior and tau dependent cytotoxicity of sequences.
Purity (HPLC) ≥75.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Pyr-FRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA |
Sequence(3-letter code) | Pyr-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH |
Peptide Structure | ![[Pyr3]-Amyloid β-Protein (3-42) 183449-57-2.png](/SupplyImg/2023-06-09/6382190476393841092167364.jpg "[Pyr3]-Amyloid β-Protein (3-42) 183449-57-2.png")
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Molecular Formula | C196H299N53O55S |
Molecular Weight | 4309.97 |
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關(guān)鍵字： [Pyr3]-Amyloid β-Pro;183449-57-2;淀粉樣蛋白;多肽;多肽合成;
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