Host:Rabbit
Target Protein:SNCA
IR:Immunogen Range:51-90/140
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:6622
Swiss Prot:P37840
Source:KLH conjugated synthetic peptide derived from human alpha-Synuclein:51-90/140
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Pig
Cow
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用!
關鍵字: SNCA;SYUA_HUMAN;MGC105443;MGC110988;MGC127560;MGC70609;MGC64356;NACP;
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