Host:Rabbit

Target Protein:Oct4

IR:Immunogen Range:

Clonality:Monoclonal

Isotype:IgG

Entrez Gene:5460

Swiss Prot:Q01860

Source:Recombinant human Oct 4 protein, around 1-100aa: 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Expression of the POU-domain transcription factor Octamer-4 (Oct-4) is widely regarded as a hallmark of pluripotent stem cells. The relationship of Oct-4 to pluripotent stem cells is indicated by its tightly restricted expression to undifferentiated pluripotent stem cells. Upon differentiation to somatic lineages, the expression of Oct-4 disappears rapidly. Unlike the majority of pluripotent stem cell markers, the biological role of Oct-4 has been well characterized. Studies performed in mice point to the critical role of Oct-4 in the establishment and/or maintenance of pluripotent stem cells in an uncommitted state.

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
IP(1:20-100)
IHC-P(1:50-200)
IHC-F(1:50-200)
ICC(1:50-200)

Cross Reactive Species:Human
Mouse
Rat