價(jià)格 | ¥1098 | ¥1880 | ¥2900 |
包裝 | 50ul | 100ul | 200ul |
最小起訂量 | 50ul |
發(fā)貨地 | 上海 |
文件下載 | 檢測(cè)報(bào)告COA |
更新日期 | 2024-12-26 |
中文名稱:Anti-ATF6 antibody-活化轉(zhuǎn)錄因子6抗體 | 英文名稱:ATF6 |
品牌: 滬震生物 | 產(chǎn)地: 中國(guó)/上海 |
保存條件: -20°C | 純度規(guī)格: > 99% |
產(chǎn)品類別: 抗體 一抗 | |
抗體名: Activating transcription factor 6 alpha; Activating transcription factor 6; ATF 6; ATF6 alpha; ATF6; ATF6-alpha; ATF6A; ATF6A_HUMAN; cAMP dependent transcription factor ATF 6 alpha; cAMP-dependent transcription factor ATF-6 alpha; Cyclic AMP dependent transcription factor ATF 6 alpha; DKFZp686P2194; ESTM49; FLJ21663; Processed cyclic AMP dependent transcription factor ATF 6 alpha; Processed cyclic AMP-dependent transcription factor ATF-6 alpha. | 靶點(diǎn): 詳見(jiàn)說(shuō)明書(shū) |
宿主: Rabbit | 適應(yīng)物種: 詳見(jiàn)說(shuō)明書(shū) |
克隆性: 詳見(jiàn)說(shuō)明書(shū) | 濃度: 1mg/ml |
應(yīng)用范圍: WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100 IF=1:100-500 (石蠟切片需做抗原修復(fù)) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. | 標(biāo)識(shí)物: 詳見(jiàn)說(shuō)明書(shū) |
形態(tài): 液體 | 亞型: IgG1 |
免疫原: 詳見(jiàn)說(shuō)明書(shū) | 貨號(hào): Hz-R23094 |
用途范圍: 科研使用 | 規(guī)格: 50ul/100ul/200ul |
是否進(jìn)口: 否 | 是否單克隆: 詳見(jiàn)說(shuō)明書(shū)p55 |
保質(zhì)期: 12個(gè)月 | 抗原來(lái)源: 詳見(jiàn)說(shuō)明書(shū) |
標(biāo)記物: 詳見(jiàn)說(shuō)明書(shū) | 產(chǎn)品用途: WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100 IF=1:100-500 (石蠟切片需做抗原修復(fù)) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
Host:Rabbit
Target Protein:ATF6
IR:Immunogen Range:431-530/670
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:22926
Swiss Prot:P18850
Source:KLH conjugated synthetic peptide derived from human ATF6:431-530/670
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:ATF6 is a transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. It binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3'). Binding to ERSE requires binding of NF-Y to ERSE. ATF6 could also be involved in activation of transcription by the serum response factor. ATF6 exists as a homodimer and heterodimer with ATF6 beta. The dimer interacts with the nuclear transcription factor Y (NF-Y) trimer through direct binding to NF-Y subunit C (NF-YC). It also interacts with the transcription factors GTF2I, YY1 and SRF. Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus. The basic domain of ATF6 functions as a nuclear localization signal and the basic leucine zipper domain is sufficient for association with the NF-Y trimer and binding to ERSE. During the unfolded protein response an approximately 50 kDa fragment containing the cytoplasmic transcription factor domain is released by proteolysis. The cleavage seems to be performed sequentially by site 1 and site 2 proteases. ATF6 is N glycosylated, phosphorylated in vitro by MAPK14/P38MAPK and belongs to the bZIP family.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Rabbit
Sheep
本產(chǎn)品僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷使用!
成立日期 | 2014-05-08 (11年) | 注冊(cè)資本 | 100萬(wàn)元整 |
員工人數(shù) | 10-50人 | 年?duì)I業(yè)額 | ¥ 100萬(wàn)以內(nèi) |
主營(yíng)行業(yè) | 生化試劑,細(xì)胞培養(yǎng),蛋白組學(xué),分子生物學(xué),細(xì)胞生物學(xué) | 經(jīng)營(yíng)模式 | 工廠,試劑,定制,服務(wù) |
產(chǎn)品名稱 | 價(jià)格 | 公司名稱 | 報(bào)價(jià)日期 | |
---|---|---|---|---|
詢價(jià) |
VIP4年
|
上海冠導(dǎo)生物工程有限公司
|
2024-12-26 | |
詢價(jià) |
VIP3年
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上海嘉定區(qū)澄瀏公路52號(hào)
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2024-12-25 | |
¥2808 |
VIP6年
|
上海澤葉生物科技有限公司
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2024-12-26 |