Host:Rabbit
Target Protein:Phospho-Lyn (Tyr397)
IR:Immunogen Range:NE(p-Y)TA
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:4067
Swiss Prot:P07948
Source:KLH conjugated synthesised phosphopeptide derived from human Lyn around the phosphorylation site of Tyr397:NE(p-Y)TA
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Lyn (also known as p53/56 Lyn) is a membrane associated protein tyrosine kinase (PTK) mostly expressed in hemopoietic cells which is important in cellular signaling. It contains an SH2 and SH3 domain and has been found to be cleaved after activation of caspases in apoptosis. A member of the Src family of PTKs, there are two known isoforms for Lyn which plays an indispensable role in the Fc epsilon RI (Fcer1) and the B cell IgM receptor signaling pathway and is essential for Syk activation and Lat phosphorylation after Fcer1 aggregation and can also phosphorylate Tec on multiple residues. Lyn can also be regulated by IL2 and IL3.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)ELISA(1:5000-10000)IHC-P(1:100-500)IHC-F(1:100-500)IF(1:100-500)
Cross Reactive Species:HumanMouseRatChickenPigRabbit
本產(chǎn)品僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷使用!
上海滬震實(shí)業(yè)有限公司
聯(lián)系商家時(shí)請(qǐng)?zhí)峒癱hemicalbook,有助于交易順利完成!
上海滬震生物