Product Name:Pramlintide
CAS No.: 151126-32-8;196078-30-5
Synonyms:醋酸普蘭林肽
Catalog No.:215P23
Brand:HongTide(上海鴻肽生物)
Description:醋酸普蘭林肽是胰淀粉樣多肽(Amylin,淀粉不溶素)的一種合成類似物,是由37個氨基酸組成的環(huán)狀多肽,是繼胰島素之后第二個獲準用于治療1型糖尿病的藥物。在臨床上,以普蘭林肽為主要原料的藥物,可用作1型和2型糖尿病的輔助治療藥物,主要用于單用胰島素,以及聯合應用胰島素和磺脲類藥物、二甲雙胍仍無法取得預期療效的糖尿病患者。實驗證明,普蘭林肽可與胰島素合用,但不能取代胰島素。
Pramlintide is a synthetic analog of pancreatic amyloid peptide (Amylin). It is a cyclic polypeptide composed of 37 amino acids. It is the second drug approved to treat type 1 diabetes after insulin. Clinically, the drug with Pranin as the main raw material can be used as an auxiliary treatment drug for type 1 and type 2 diabetes. It is mainly used for diabetes patients who can not achieve the expected effect with insulin alone, insulin and sulfonylurea drugs in combination, and metformin. Experiments have shown that planin can be used in combination with insulin, but it cannot replace insulin.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | KCNTATCATQRLANFLVHSSNNFGPILPPTNVGSNTY-NH2(Disulfide bridge: Cys2-Cys7) |
Sequence(3-letter code) | H-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Pro-Ile-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2(Disulfide bridge: Cys2-Cys7) |
Peptide Structure |
|
Molecular Formula | C171H267N51O53S2 |
Molecular Weight | 3949.44 |
訂購聯系方式:
上海鴻肽生物科技有限公司
手機: +86-18018095145 (同微信號)
QQ: 3259098395
郵箱:sales1@hongtide.com
關鍵字: 151126-32-8;醋酸普蘭林肽;Pramlintide;196078-30-5;多肽合成;
上海鴻肽生物科技有限公司(簡稱:鴻肽生物)是一家以多肽以及多肽上下游產品研發(fā)、生產、銷售以及技術轉讓為主要業(yè) 務科技公司。公司現有產品涵蓋:定制多肽、目錄多肽、氨基酸衍生物、小分子化合物;公司自成立以來,秉持“用質量作船, 以服務為帆,為科研服務”的企業(yè)理念,為國內外眾多科研工作者提供了優(yōu)質的服務及產品。