Host:Rabbit
Target Protein:IKK gamma
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:8517
Swiss Prot:Q9Y6K9
Source:Recombinant human IKK gamma protein:
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Pro inflammatory cytokines activate the transcription factor NF kappa B by stimulating the activity of a protein kinase that phosphorylates Ikappa B, an inhibitor of NF kappa B, at sites that trigger its ubiquitination and degradation. A large, cytokine responsive Ikappa B kinase (IKK) complex has been purified and the genes encoding 2 of its subunits have been cloned. These subunits, IKK alpha and Ikk beta, are protein kinases whose function is needed for NF kappa B activation by pro inflammatory stimuli. IKK is composed of similar amounts of IKK alpha, Ikk beta, which are differentially processed forms of a third subunit, IKK gamma. IKK gamma interacts preferentially with IKK beta and is required for the activation of the IKK complex.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
IHC-P(1:20-50)
IHC-F(1:20-50)
ICC(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
本產(chǎn)品僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷使用!
關(guān)鍵字: AMCBX1;FIP3;Fip3p;IKKAP1;IKKG;
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