Product Name：HIV Integrase Protein Inhibitor(1)
CAS No.：172546-75-7
Synonyms：HIV編碼整合酶(IN)抑制劑多肽
Catalog No.：162P12
Brand：HongTide（上海鴻肽生物）
Description：HIV編碼整合酶(IN)的有效抑制劑多肽，由6個(gè)氨基酸組成的多肽，該酶負(fù)責(zé)將 HIV DNA 整合到人類基因組中。HIV Integrase Protein Inhibitor(1)能抑制 IN 介導(dǎo)的 3' 加工和整合，IC 為 2 μM。 該肽對(duì)來自其他逆轉(zhuǎn)錄病毒如 HIV-2、貓免疫缺陷病毒和莫洛尼鼠白血病病毒的 IN 蛋白也有活性。 還發(fā)現(xiàn)它可以抑制分解反應(yīng)，這表明這種六肽作用于 IN 的催化位點(diǎn)處或附近。
HIV encodes an effective inhibitor peptide of integrase (IN), a peptide composed of six amino acids, which is responsible for integrating HIV DNA into the human genome. HIV Integrate Protein Inhibitor (1) can inhibit IN mediated 3 'processing and integration, with an IC of 2 μ M. This peptide also has activity against IN proteins from other retroviruses such as HIV-2, feline immunodeficiency virus, and Moroni mouse leukemia virus. It was also found that it can inhibit the decomposition reaction, indicating that this hexapeptide acts at or near the catalytic site of IN.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | HCKFWW |
Sequence(3-letter code) | H-His-Cys-Lys-Phe-Trp-Trp-OH |
Peptide Structure | 
|
Molecular Formula | C46H55N11O7S |
Molecular Weight | 906.07 |
訂購(gòu)聯(lián)系方式：
上海鴻肽生物科技有限公司
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郵箱：sales1@hongtide.com
關(guān)鍵字： 172546-75-7;HIV Integrase Protei;HIV編碼整合酶(IN)抑制劑多肽?;多肽;多肽合成;
上海鴻肽生物科技有限公司（簡(jiǎn)稱：鴻肽生物）是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋：定制多肽、目錄多肽、氨基酸衍生物、小分子化合物；公司自成立以來，秉持“用質(zhì)量作船， 以服務(wù)為帆，為科研服務(wù)”的企業(yè)理念，為國(guó)內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。