Product Name：LL-37 FKR
CAS No.：913736-94-4
Synonyms：LL-37 (17-37)；Cationic Antimicrobial Protein 18 (150-170) (human),hCAP-18 (150-170)；人源性抗菌肽LL-37 FKR
Catalog No.：112P47
Brand：HongTide（上海鴻肽生物）
Description：LL-37 是人體內(nèi)發(fā)現(xiàn)的唯一的一種Cathelicidin 類(lèi)抗菌肽，LL-37是由前體hCAP-18 經(jīng)絲氨酸蛋白酶3剪切后產(chǎn)生。大量研究發(fā)現(xiàn)，LL-37 可在卵巢癌、肺癌、惡性黑色素瘤、皮膚鱗狀細(xì)胞癌、前列腺癌等腫瘤中發(fā)揮促癌作用；而在胃癌、結(jié)直腸癌、白血病等腫瘤中發(fā)揮抑癌作用，因此對(duì)LL-37的研究具有很大的潛力。LL-37 FKR是從LL-37序列中選取第17個(gè)氨基酸至第37個(gè)氨基酸片段，保留了大部分的生理學(xué)功能。
LL-37 is the only Catalicidin class antimicrobial peptide found in the human body, and is produced by the precursor hCAP-18 after being cleaved by serine protease 3. A large number of studies have found that LL-37 can play a cancer promoting role in ovarian cancer, lung cancer, malignant melanoma, skin squamous cell carcinoma, prostate cancer and other tumors; And it plays an inhibitory role in tumors such as gastric cancer, colorectal cancer, and leukemia, so the research on LL-37 has great potential. LL-37 FKR selects the 17th to 37th amino acid fragments from the LL-37 sequence, preserving most of its physiological functions.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | FKRIVQRIKDFLRNLVPRTES |
Sequence(3-letter code) | H-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH |
Peptide Structure | 
|
Molecular Formula | C118H199N37O30 |
Molecular Weight | 2616.11 |
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關(guān)鍵字： LL-37 FKR;913736-94-4;源性抗菌肽LL-37 FKR;抗菌肽;多肽;
上海鴻肽生物科技有限公司（簡(jiǎn)稱(chēng)：鴻肽生物）是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷(xiāo)售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋：定制多肽、目錄多肽、氨基酸衍生物、小分子化合物；公司自成立以來(lái)，秉持“用質(zhì)量作船， 以服務(wù)為帆，為科研服務(wù)”的企業(yè)理念，為國(guó)內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。