Product Name：Fz7-21
CAS No.：2247635-23-8
Synonyms：拮抗劑多肽Fz7-21
Catalog No.：218P101
Brand：HongTide（上海鴻肽生物）
Description：Fz7-21是一種FZD7（FZD7）受體的肽拮抗劑，由14個氨基酸組成，肽鏈的兩端均被封閉，選擇性地與FZD7-CRD亞類結合。人和小鼠FZD7-CRD的EC50值分別為58和34nm。Fz7-21在外源性WNT3A（IC50=100?nM）刺激或轉(zhuǎn)染表達WNT3A或WNT1的HEK293細胞中削弱Wnt/β-catenin信號傳導。小鼠β2 1-3nM細胞的穩(wěn)定化作用。
Fz7-21 is a peptide antagonist of the FZD7 (FZD7) receptor, composed of 14 amino acids, with both ends of the peptide chain blocked and selectively binding to the FZD7-CRD subclass. The EC50 values of human and mouse FZD7-CRD were 58 and 34 nm, respectively. Fz7-21 attenuates Wnt in HEK293 cells expressing WNT3A or WNT1 stimulated or transfected with exogenous WNT3A (IC50=100 nM)/ β- Catenin signal transduction. mice β The stabilization effect of 2 1-3nM cells.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Ac-LPSDDLEFWCHVMY-NH2 |
Sequence(3-letter code) | Ac-Leu-Pro-Ser-Asp-Asp-Leu-Glu-Phe-Trp-Cys-His-Val-Met-Tyr-NH2 |
Peptide Structure | 
|
Molecular Formula | C83H114N18O23S2 |
Molecular Weight | 1796.04 |
訂購聯(lián)系方式：
上海鴻肽生物科技有限公司
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郵箱：sales1@hongtide.com
關鍵字： 2247635-23-8;Fz7-21;拮抗劑多肽Fz7-21;多肽合成;多肽;
上海鴻肽生物科技有限公司（簡稱：鴻肽生物）是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術轉(zhuǎn)讓為主要業(yè) 務科技公司。公司現(xiàn)有產(chǎn)品涵蓋：定制多肽、目錄多肽、氨基酸衍生物、小分子化合物；公司自成立以來，秉持“用質(zhì)量作船， 以服務為帆，為科研服務”的企業(yè)理念，為國內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務及產(chǎn)品。