Product Name:K 41498
CAS No.:434938-41-7
Synonyms:CRF2受體拮抗劑多肽
Catalog No.:217P621
Brand:HongTide(上海鴻肽)
Description:K 41498是一種有效且高度選擇性的CRF2受體拮抗劑(對(duì)人CRF2α、CRF2β和CRF1受體的Ki值分別為0.66、0.62和425nM)多肽,序列中含有30個(gè)氨基酸,其中有兩個(gè)是非天然氨基酸。K 41498能抑制suvagine刺激的cAMP在hCRF2α和hCRF2β表達(dá)細(xì)胞中的積累。在大鼠體內(nèi),全身給藥后阻斷尿皮質(zhì)素誘導(dǎo)的低血壓。
Purity (HPLC) ≥95.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code)
d-FHLLRK-Nle-IEIEKQEKEKQQAANNRLLLDTI-NH2
Sequence(3-letter code)
H-D-Phe-His-Leu-Leu-Arg-Lys-Nle-Ile-Glu-Ile-Glu-Lys-Gln-Glu-Lys-Glu-Lys-Gln-Gln-Ala-Ala-Asn-Asn-Arg-Leu-Leu-Leu-Asp-Thr-Ile-NH2
Peptide Structure
Molecular Formula
C162H276N48O46
Molecular Weight
3632.26
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鴻肽生物