產(chǎn)品屬性:
產(chǎn)品名稱
規(guī)格
CAS號
型號
Desmethyl Bosentan
500 μg 1 mg 5 mg
253688-61-8
EY-Y0164905
Cas No.253688-61-8
別名 N/A
化學(xué)名 N/A
分子式 C26H27N5O6S
分子量 537.6
溶解度 Acetonitrile: soluble,DMSO: soluble,Methanol: soluble
儲存條件 Store at-20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request 產(chǎn)品描述: Desmethyl bosentan is an active metabolite of the endothelin receptor antagonist bosentan .1 Desmethyl bosentan (25 μM) activates the pregnane X receptor (PXR) in CV-1 monkey kidney cells expressing the human receptor in a reporter assay.
1.van Giersbergen, P.L.M., Gnerre, C., Treiber, A., et al.Bosentan, a dual endothelin receptor antagonist, activates the pregnane X nuclear receptorBr. J. Clin. Pharmacol.54(5)561-562(2002)
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