產(chǎn)品屬性:
產(chǎn)品名稱
規(guī)格
CAS號
型號
HIV-1 integrase inhibitor 3
1mg 5mg 10mg
1638504-56-9
EY-Y0164622
Cas No.1638504-56-9
別名 N/A
化學名 N/A
分子式 C21H22F2N4O4
分子量 432.42
溶解度 Soluble in DMSO
儲存條件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request 產(chǎn)品描述: HIV-1 integrase inhibitor 3 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM. IC50: 2.7 nM (INST)[1]
HIV-1 integrase inhibitor 3 (compound 4c) is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM. HIV-1 integrase inhibitor 3 also displays an antiviral inhibitory potency against the Q148H/G140S mutant with an EC50 of 7 nM[1].
[1]. Zhao XZ, et al. HIV-1 Integrase Strand Transfer Inhibitors with Reduced Susceptibility to Drug Resistant MutantIntegrases. ACS Chem Biol. 2016 Apr 15;11(4):1074-81.
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