產(chǎn)品屬性:
產(chǎn)品名稱
規(guī)格
CAS號(hào)
型號(hào)
CMI977 (LDP977)
10mg 5mg 1mg
175212-04-1
EY-Y0164082
Cas No.175212-04-1
別名 N/A
化學(xué)名 N/A
分子式 C16H19FN2O4
分子量 322.33
溶解度 Soluble in DMSO
儲(chǔ)存條件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request 產(chǎn)品描述: CMI977 is a potent 5-Lipoxygenase (5-LO) inhibitor.
CMI977 is a potent 5-lipoxygenase (5-LO) inhibitor that intervenes in the production of leukotrienes and is presently being developed for the treatment of chronic asthma. It is a single enantiomer with an all-trans (2S,5S) configuration. Of the four isomers of CMI977, the S,S isomer is found to have the best biological activity and is selected for further development.
[1]. Xiong Cai, et al. Synthesis of CMI-977, a Potent 5-Lipoxygenase Inhibitor. Org. Proc. Res. Dev., 1999, 3 (1), pp 73-76.
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