產(chǎn)品屬性:
產(chǎn)品名稱(chēng)
規(guī)格
CAS號(hào)
型號(hào)
CC-92480
100mg 50mg 200g 5mg 10mg 500mg
2259648-80-9
EY-Y0164020
Cas No.2259648-80-9
別名 N/A
化學(xué)名 N/A
分子式 C32H30FN5O4
分子量 567.61
溶解度 DMSO: 5 mg/mL (8.81 mM; ultrasonic and warming and heat to 60°C)
儲(chǔ)存條件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request 產(chǎn)品描述: CC-92480 is a cereblon E3 ubiquitin ligase modulating drug (CELMoD). CC-92480 shows high affinity to cereblon, resulting in potent antimyeloma activity[1].
[1]. Nooka AK, et al. Mechanism of Action and Novel IMiD-Based Compounds and Combinations in Multiple Myeloma. Cancer J. 2019 Jan/Feb;25(1):19-31.
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