產品屬性:
產品名稱 | 規(guī)格 | CAS號 | 型號 |
Beauvericin | 1mg 5mg 10mg | 26048-05-5 | EY-Y0163919 |
Cas No.26048-05-5
別名 N/A
化學名 (3S,9S,15S)-3,9,15-tribenzyl-6,12,18-triisopropyl-4,10,16-trimethyl-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexaone
分子式 C45H57N3O9
![Beauvericin.png Beauvericin.png](/SupplyImg/2022-11-22/6380472758889005099324633.jpg)
分子量 783.95
溶解度 DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml
儲存條件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述:
Beauvericin is a mycotoxin originally derived from B. bassiana, a common fungal parasite of arthropods. It is also produced by the fungus Fusarium, a pathogen of insects and plants.[1] Beauvericin is cytotoxic against insect cells, killing the insect cell line SF-9 with a 50% cytotoxic concentration of 2.5 μM.[2] In mammalian cells, beauvericin induces apoptosis with an IC50 value of 4.5 μM.[1],[3]
Reference:
[1]. Logrieco, A., Moretti, A., Castella, G., et al. Beauvericin production by Fusarium species. Applied and Environmental Microbiology 64(8), 3084-3088 (1998).
[2]. Calo, L., Fornelli, F., Nenna, S., et al. Beauvericin cytotoxicity to the invertebrate cell line SF-9. J.Appl.Genet. 44(4), 515-520 (2003).
[3]. Tonshin, A.A., Teplova, V.V., Andersson, M.A., et al. The Fusarium mycotoxins enniatins and beauvericin cause mitochondrial dysfunction by affecting the mitochondrial volume regulation, oxidative phosphorylation and ion homeostasis. Toxicology 276, 49-57 (2010).
關鍵字: 26048-05-5;C45H57N3O9;Beauvericin;
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