中文名稱:Atorvastatin-d5 (calcium salt) | 英文名稱:Atorvastatin-d5 (calcium salt) |
CAS:222412-82-0 | 品牌: 一研 |
保存條件: Store at -20°C | 產(chǎn)品類別: 抑制劑 |
Cas : 222412-82-0 |
產(chǎn)品屬性:
產(chǎn)品名稱 | 規(guī)格 | CAS號 | 型號 |
Atorvastatin-d5 (calcium salt) | 500μg 1mg | 222412-82-0 | EY-Y0163878 |
Cas No.222412-82-0
別名 N/A
化學名 N/A
分子式 C29H30D5FN2O5.1/2Ca
分子量 582.7
溶解度 DMF: 25 mg/ml,DMSO: 15 mg/ml,Ethanol: 0.50 mg/ml
儲存條件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
Atorvastatin-d5 is intended for use as an internal standard for the quantification of atorvastatin by GC- or LC-MS. Atorvastatin is an inhibitor of HMG-CoA reductase, the rate-limiting enzyme in the mevalonate pathway of cholesterol synthesis, that has IC50 values of 73, 102, and 0.6 nM for HepG2 cells, human fibroblasts, and rat hepatocytes, respectively.1 Formulations containing atorvastatin have been used in the treatment of hypercholesterolemia and certain dyslipidemias.
1.Shaw, M.K., Newton, R.S., Sliskovic, D.R., et al.Hep-G2 cells and primary rat hepatocytes differ in their response to inhibitors of HMG-CoA reductaseBiochem. Biophys. Res. Commun.170(2)726-734(1990)
成立日期 | 2014-06-05 (11年) | 注冊資本 | 100 |
員工人數(shù) | 50-100人 | 年營業(yè)額 | ¥ 100萬以內(nèi) |
主營行業(yè) | 生化試劑,抗體,細胞培養(yǎng),分子生物學,免疫安全 | 經(jīng)營模式 | 工廠,試劑 |
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