產(chǎn)品屬性:
產(chǎn)品名稱 | 規(guī)格 | CAS號(hào) | 型號(hào) |
Acetylcholine Chloride | 5mg 10mg 25mg 50mg | 362049-62-5 | EY-Y0163728 |
Cas No.362049-62-5
別名 N/A
化學(xué)名 N/A
分子式 C9H15D3NO4.Cl
分子量 242.7
溶解度 Methanol: slightly soluble,Water: soluble
儲(chǔ)存條件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
Acetyl-L-carnitine-d3 is intended for use as an internal standard for the quantification of L-acetylcarnitine by GC- or LC-MS. Acetyl-L-carnitine is an acetylated form of the essential mitochondrial metabolite L-carnitine that is catabolized by plasma esterases into carnitine.1,2,3 Acetyl-L-carnitine facilitates the uptake of acetyl-CoA into mitochondria during fatty acid oxidation, enhances acetylcholine production, and stimulates protein and membrane phospholipid synthesis. In vivo, acetyl-L-carnitine (100 mg/kg) increases mGlu2/3 receptor protein levels and mechanical pain thresholds in a mouse model of chronic inflammatory pain induced by complete Freund's adjuvant.4
1.Vaz, F.M., and Wanders, R.J.A.Carnitine biosynthesis in mammalsBiochem. J.361(Pt 3)417-429(2002) 2.Fu, L., Huang, M., and Chen, S.Primary carnitine deficiency and cardiomyopathyKorean. Circ. J.43(12)785-792(2013) 3.Stieger, B., O'Neill, B., and Kr?henbühl, S.Characterization of L-carnitine transport by rat kidney brush-border-membrane vesiclesBiochemistry Journal309(Pt 2)643-647(1995) 4.Notartomaso, S., Mascio, G., Bernabucci, M., et al.Analgesia induced by the epigenetic drug, L-acetylcarnitine, outlasts the end of treatment in mouse models of chronic inflammatory and neuropathic painMol. Pain13:1744806917697009(2017)
關(guān)鍵字: 362049-62-5;C9H15D3NO4.Cl;Acetylcholine Chlori;
上海一研生物科技有限公司Shanghai yiyan bio-technology Co. Ltd.主要從事免疫學(xué)、分子生物學(xué)和常規(guī)生化試劑等為一體的科研產(chǎn)品銷售企業(yè),公司自成立以來(lái),秉承""全心全意服務(wù)于科研工作者""的企業(yè)理念,立足生物科技領(lǐng)域,運(yùn)用生物技術(shù)和科研試劑,發(fā)展現(xiàn)代生物科技,為各類大中小醫(yī)院及其它醫(yī)療機(jī)構(gòu)、高等院校、科研院所、企事業(yè)單位提供優(yōu)質(zhì)的產(chǎn)品,服務(wù)生物科技領(lǐng)域的科學(xué)研究人員。
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