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[2]. Leach, M.J., C.M. Marden, and A.A. Miller, Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action. Epilepsia, 1986. 27(5): p. 490-7.

[3]. Cheung, H., D. Kamp, and E. Harris, An in vitro investigation of the action of lamotrigine on neuronal voltage-activated sodium channels. Epilepsy Res, 1992. 13(2): p. 107-12.

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1、 摩爾折射率：63.38

2、 摩爾體積（cm3/mol）：162.8

3、 等張比容（90.2K）：486.4

4、 表面張力（dyne/cm）：79.6

5、 極化率（10-24cm3）：25.12

1.疏水參數(shù)計算參考值（XlogP）:1.4

2.氫鍵供體數(shù)量:2

3.氫鍵受體數(shù)量:5

4.可旋轉化學鍵數(shù)量:1

5.互變異構體數(shù)量:9

6.拓撲分子極性表面積90.7

7.重原子數(shù)量:16

8.表面電荷:0

9.復雜度:242

10.同位素原子數(shù)量:0

11.確定原子立構中心數(shù)量:0

12.不確定原子立構中心數(shù)量:0

13.確定化學鍵立構中心數(shù)量:0

14.不確定化學鍵立構中心數(shù)量:0

15.共價鍵單元數(shù)量:1

1.性狀：白色至淡奶色粉末,從異丙醇結晶.

2.熔點：216-218℃.