效能
420?mg/kg LD50, oral (Rat)2900?mg/kg LD50, skin (Rabbit)
一般描述
Diisopropylamine (DIPA) is an aliphatic secondary amine commonly used as an organic base in chemical synthesis.
應用
Diisopropylamine can be used as: A reagent to synthesize furan, dihydrofuran, or butanolide derivatives by reacting with γ-ketothioesters. A catalyst to prepare aryl disulfides via oxidative coupling of aryl thiols in the presence of air as an oxidant. A base in Pd-catalyzed cross-coupling reactions such as Heck and Sonogashira reaction. It can also be used as a starting material to prepare lithium diisopropylamide (LDA), a strong non-nucleophilic base widely used in organic synthesis for deprotonation reactions.
Sigma-Aldrich西格瑪奧德里奇(上海)貿易有限公司
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