中文名稱

【FSH】人卵泡刺激素

英文名字

Human Follicle Stimulating Hormone

供應(yīng)商

ProSpec

產(chǎn)品貨號(hào)

HOR-249

背景資料

Follicle stimulating hormone （FSH） is a hormone synthesised and secreted by gonadotropes in the anterior pituitary gland. FSH and LH act synergistically in reproductionIn women， in the ovary FSH stimulates the growth of immature Graafian follicles to maturation. As the follicle grows it releases inhibin， which shuts off the FSH production.
In men， FSH enhances the production of androgen-binding proteinby the Sertoli cells of the testes and is critical for spermatogenesis.
In both males and females， FSH stimulates the maturation of germ cells. In females， FSH initiates follicular growth， specifically affecting granulosa cells. With the concomitant rise in inhibin B FSH levels then decline in the late follicular phase. This seems to be critical in selecting only the most advanced follicle to proceed to ovulation. At the end of the luteal phase， there is a slight rise in FSH that seems to be of importance to start the next ovulatory cycle.
Like its partner， LH， FSH release at the pituitary gland is controlled by pulses of gonadotropin-releasing hormone（GnRH）. Those pulses， in turn， are subject to the estrogen feed-back from the gonads.

序列

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來(lái)源宿主

Urine of post-menopausal women.

溶解建議

提供的人卵泡刺激素產(chǎn)品為白色無(wú)菌凍干粉末，凍干粉里不含有其它添加劑.推薦使用無(wú)菌的18MΩ的超純水來(lái)溶解，濃度不低于100ug/ml，便于后續(xù)稀釋.

保存建議

Lyophilized FSH although stable at room temperature for 3 weeks， should be stored desiccated below -18℃. Upon reconstitution FSH-beta should be stored at 4℃ between 2-7 days and for future use below -18℃. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles.

其他

ProSpec 是一家全球著名細(xì)胞因子蛋白生產(chǎn)和研發(fā)的公司，具有20多年的生產(chǎn)經(jīng)驗(yàn)，專注于蛋白（重組及合成）生產(chǎn)研發(fā)。我們的核心產(chǎn)品包括：干擾素、白介素、骨蛋白、腫瘤壞死因子、成纖維生長(zhǎng)因子、瘦素、干細(xì)胞因子、催乳素、表皮生長(zhǎng)因子、胰島素樣生長(zhǎng)因子、神經(jīng)生長(zhǎng)因子、集落刺激因子、激素、酶、病毒抗原以及各種重組蛋白等。 領(lǐng)先的生產(chǎn)工藝和規(guī)模使其可以提供毫克到克級(jí)蛋白，價(jià)格優(yōu)于同類公司。絕大部分產(chǎn)品是天然成熟型蛋白，而不含有標(biāo)簽蛋白?？紤]到大部分研究者希望能更靈活地配制蛋白溶液，ProSpec-Tany絕大部分產(chǎn)品沒(méi)有添加保護(hù)劑或鹽，這就對(duì)工藝提出了更高的要求。同時(shí)，ProSpec-Tany絕大部分產(chǎn)品為凍干粉，因此易于運(yùn)輸和保存。