中文名稱

N'-[4'-（二甲基氨基）[1，-1'-聯(lián)苯] -3-3-基] -N，N-二甲基脲

英文名字

N’-[4’-(dimethylamino)[1,1’-biphenyl]-3-yl]-N,N-dimethyl-urea

供應(yīng)商

開曼生物

產(chǎn)品貨號(hào)

15284-10

背景資料

Adipose triglyceride lipase (ATGL or PNPLA2) catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets, generating diacylglyerol.{21269,21272} Atglistatin is a potent, selective, and competitive inhibitor of ATGL (IC50 = 0.7 μM).{24582} It does not inhibit hormone-sensitive lipase, monoglyceride lipase, pancreatic lipase, lipoprotein lipase, or other lysophospholipases.{24582} Atglistatin blocks lipolysis by ATGL in vitro, in white adipose tissue organ cultures, and in vivo.{24582} It does not affect lipolysis in ATGL knockout mice.{24582}

產(chǎn)品描述

A potent, selective, and competitive inhibitor of ATGL (IC50 = 0.7 μM); does not inhibit hormone-sensitive lipase, monoglyceride lipase, pancreatic lipase, lipoprotein lipase, or other lysophospholipases; blocks lipolysis by ATGL in vitro, in white adipose tissue organ cultures, and in vivo

保存建議

建議您在收到開曼生物品牌的Atglistatin (10 mg)產(chǎn)品后置于-20度保存，產(chǎn)品有效期為730天.

其他

開曼生物向全球科學(xué)工作者提供多研究領(lǐng)域的生化、免疫試劑和分析試劑盒，其產(chǎn)品被廣泛應(yīng)用于腫瘤、氧化氮、神經(jīng)學(xué)、凋亡、氧化性損傷、內(nèi)分泌學(xué)等不同研究領(lǐng)域.開曼生物可提供用于檢測(cè)的特色試劑盒，如：類花生酸類物質(zhì)、游離的生物標(biāo)志、環(huán)核苷、激素及氧化氮等；也提供多種高質(zhì)量試劑，包括：類花生酸類物質(zhì)、氧化氮試劑及許多相關(guān)脂質(zhì)、脂肪酸、酶和抗體.