中文名稱

PAK 磁珠，Rac1/Cdc42 結(jié)合域蛋白磁珠

英文名字

PAK Beads, Rac1/Cdc42 binding domain protein on beads

供應(yīng)商

Cytoskeleton

產(chǎn)品貨號(hào)

PAK02-A

背景資料

該P(yáng)AK 磁珠，Rac1/Cdc42 結(jié)合域蛋白磁珠產(chǎn)品是Cytoskeleton品牌原裝進(jìn)口，Cytoskeleton品牌是細(xì)胞骨架研究專家，專注于生物化學(xué)和細(xì)胞過(guò)程研究中的純化蛋白和便捷試劑盒開(kāi)發(fā)與生產(chǎn)。 

產(chǎn)品描述

The Rac/Cdc42 (p21) binding domain (PBD) of the human p21 activated kinase 1 protein (PAK) protein has been expressed as a GST-fusion protein in E. coli. This protein binds binds specifically to GTP-bound, and not GDP-bound, Rac and Cdc42 proteins. The domain can therefore be used to specifically precipitate active, GTP-bound Rac and Cdc42 as well as to specifically block the activity of Rac and Cdc42 in vitro and in vivo.nThe GST-PAK-PBD contains residues 67-150 of PAK. This region includes the highly conserved CRIB motif plus sequences required for the high affinity interaction with GTP-Rac and GTP-Cdc42.nThe protein is supplied in a glutathione agarose bound format and is shipped lyophilized. The beads are colored for ease of use. This product is used in our Cdc42 and Rac activation assay Biochem Kits? (Cat. # BK034 and BK035, repectively). The GST-PAK-PBD is also available as a free protein (Cat. # PAK01).

產(chǎn)品形式

該P(yáng)AK 磁珠，Rac1/Cdc42 結(jié)合域蛋白磁珠產(chǎn)品是Cytoskeleton品牌的原裝進(jìn)口產(chǎn)品，具體的產(chǎn)品形式查看英文產(chǎn)品說(shuō)明書(shū)。

保存建議

廠家推薦常溫運(yùn)輸，收到產(chǎn)品后建議保存于4°C。

其他

Cytoskeleton公司成立于1993年，專注于生物化學(xué)和細(xì)胞過(guò)程研究中的純化蛋白和便捷試劑盒開(kāi)發(fā)與生產(chǎn)。公司提供藥物篩選、信號(hào)轉(zhuǎn)導(dǎo)、蛋白質(zhì)轉(zhuǎn)錄后修飾（PTM）、細(xì)胞骨架研究相關(guān)的系列試劑盒和產(chǎn)品，尤其以細(xì)胞骨架相關(guān)研究見(jiàn)長(zhǎng)，既能滿足于樣品較少的科學(xué)研究，也可以用于小規(guī)模篩選研究和高通量大規(guī)模篩選研究。此外，公司還提供微管蛋白，肌動(dòng)蛋白，小G蛋白，GAPs，GEFs等現(xiàn)有產(chǎn)品的藥物篩選服務(wù)。