中文名稱

雙唾液酸神經節(jié)苷脂GD1b（NH4 +鹽）

英文名字

Disialoganglioside GD1b (NH4+ salt)

供應商

Matreya

產品貨號

1501-1

背景資料

Gangliosides1 are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis, and metastasis.2 The accumulation of gangliosides has been linked to several diseases including Tay-Sachs and Sandhoff disease. An autoimmune response against gangliosides can lead to Guillain-Barre syndrome. High levels of GD1b are found in the gliomas and astrocytomas. It can inhibit the efflux of K+ through K+ channels which results in the suppression of apoptosis.3 GD1b acts as a bacterial toxin receptor for tetanus and botulinus as well as for the BK virus.4

產品描述

GD1b

產品形式

該雙唾液酸神經節(jié)苷脂GD1b（NH4 +鹽）產品為固體形式

保存建議

對于本產品，我們推薦使用-20℃藍冰低溫進行運輸。在您收到貨物后，我們建議在-20℃溫度下冷凍保存，溶解使用說明請參考本品說明書。