Description: AMG-131 is a hypoglycemic agent. It is a potent PPARγ partial agonist that displays robust glucose-lowering activity in rodent models of diabetes while exhibiting a reduced side-effects profile compared to marketed TZDs.
Name: AMG-131
CAS#: 315224-26-1
Chemical Formula: C21H12Cl4N2O3S
Exact Mass: 511.93227
Molecular Weight: 514.21
Elemental Analysis: C, 49.05; H, 2.35; Cl, 27.58; N, 5.45; O, 9.33; S, 6.24`
Synonym: AMG-131; AMG 131; AMG131; INT-131; NT-131; INT-131; T-0903131; T-131; ibrigampar
IUPAC/Chemical Name: Benzenesulfonamide, 2,4-dichloro-N-(3,5-dichloro-4-(3-quinolinyloxy)phenyl)-
InChi Key: NMRWDFUZLLQSBN-UHFFFAOYSA-N
InChi Code: InChI=1S/C21H12Cl4N2O3S/c22-13-5-6-20(16(23)8-13)31(28,29)27-14-9-17(24)21(18(25)10-14)30-15-7-12-3-1-2-4-19(12)26-11-15/h1-11,27H
SMILES Code: c1ccc2c(c1)cc(cn2)Oc3c(cc(cc3Cl)NS(=O)(=O)c4ccc(cc4Cl)Cl)Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
關鍵字： 315224-26-1;AMG-131;
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