IRDye 800CW RGD Optical Probe
IRDye 800CW RGD 光學(xué)探頭
IRDye 800CW RGD 光學(xué)探頭是一種 BrightSite? 近紅外 (NIR) 熒光標(biāo)記的 RGD 顯像劑,專門設(shè)計(jì)用于靶向上整合素的過(guò)度表達(dá)。
整聯(lián)蛋白是細(xì)胞表面異二聚體糖蛋白,參與細(xì)胞與細(xì)胞和細(xì)胞與基質(zhì)的相互作用。 IRDye 800CW RGD 光學(xué)探針由識(shí)別基序 RGD (Arg-Gly-Asp) 組成,這是一個(gè)三肽序列,用于結(jié)合包括 αvβ3 在內(nèi)的整聯(lián)蛋白受體。
IRDye 800CW RGD Optical Probe is a BrightSite? near-infrared (NIR) fluorescently-labeled RGD imaging agent specifically designed to target the overexpression of integrins on tumors.
Integrins are cell surface heterodimeric glycoproteins involved in cell-to-cell and cell-to-matrix interactions. IRDye 800CW RGD Optical Probe is composed of the recognition motif, RGD (Arg-Gly-Asp), a tripeptide sequence used to bind integrin receptors including αvβ3. This receptor class is involved in tumor growth, tumor invasiveness, metastasis, tumor induced angiogenesis, inflammation, osteoporosis, and rheumatoid arthritis.
關(guān)鍵字: IRDye 800CW;光學(xué)探頭;
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