Name: MHAPC-Chol
CAS#: 1027801-74-6
Chemical Formula: C34H60N2O3
Exact Mass: 544.4604
Molecular Weight: 544.86
Elemental Analysis: C, 74.95; H, 11.10; N, 5.14; O, 8.81
Description: MHAPC-Chol is a cationic cholesterol. MHAPC-Chol, as part of a lipoplex with DOPE, has been used for siRNA delivery and gene silencing in MCF-7 cells in a luciferase assay without affecting cell viability. It has also been used to deliver siRNA into mice via intravenous injection, resulting in MHAPC-chol accumulation in the liver.
IUPAC/Chemical Name: (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl (3-((2-hydroxyethyl)(methyl)amino)propyl)carbamate
InChi Key: XNSUBQXPLPQEHC-DYQRUOQXSA-N
InChi Code: InChI=1S/C34H60N2O3/c1-24(2)9-7-10-25(3)29-13-14-30-28-12-11-26-23-27(39-32(38)35-19-8-20-36(6)21-22-37)15-17-33(26,4)31(28)16-18-34(29,30)5/h11,24-25,27-31,37H,7-10,12-23H2,1-6H3,(H,35,38)/t25-,27+,28+,29-,30+,31+,33+,34-/m1/s1
SMILES Code: C[C@H](CCCC(C)C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](OC(NCCCN(C)CCO)=O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C
Appearance: Solid powder
關(guān)鍵字： 1027801-74-6;MHAPC-Chol;
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