中文名稱
過氧亞硝酸鹽處理的牛血清白蛋白;硝基酪氨酸牛血清白蛋白
英文名字
Peroxynitrite-treated BSA; Nitrotyrosine BSA
供應(yīng)商
開曼生物
產(chǎn)品貨號
89542-200
產(chǎn)品報價
¥2632.8/200ug
產(chǎn)品說明書
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購買方式
銀行轉(zhuǎn)賬、電匯、支票、現(xiàn)金,在線支付寶及網(wǎng)銀支付,或直接與我們電話聯(lián)系400-6800-868
產(chǎn)品新聞
背景資料
This product can be used as a positive control for immunoblotting experiments using 開曼生物’s Nitrotyrosine Polyclonal Antibody (Catalog No. 189540) and Nitrotyrosine Monoclonal Antibody (Catalog No. 189542). Nitric oxide (NO) is a product of the enzymatic conversion of arginine to citrulline by nitric oxide synthase. NO reacts rapidly with superoxide (6.7 x 109 M-1sec-1) to form peroxynitrite. At physiological pH and in the presence of transition metals, peroxynitrite undergoes heterolytic cleavage to form hydroxyl anion and nitronium ion, the latter of which nitrates protein tyrosine residues. Thus, the presence of nitrotyrosine on proteins can be used as a marker for peroxynitrite formation in vivo. Nitrotyrosine has been shown to be present in proteins from a variety of clinical conditions including atherosclerotic lesions of human coronary arteries, postischemic heart, and placenta during preeclampsia. Increased nitration of proteins in motor neurons has been identified in patients with amyotrophic lateral sclerosis and may be due to mutations in superoxide dismutase.
產(chǎn)品描述
Nitrotyrosine BSA is a positive control for detection of protein tyrosine nitration by WB using nitrotyrosine antibodies.{5439}
保存建議
建議您在收到開曼生物品牌的Nitrotyrosine BSA (200 ug)產(chǎn)品后置于-80度保存,產(chǎn)品有效期為730天.
其他
開曼生物向全球科學(xué)工作者提供多研究領(lǐng)域的生化、免疫試劑和分析試劑盒,其產(chǎn)品被廣泛應(yīng)用于腫瘤、氧化氮、神經(jīng)學(xué)、凋亡、氧化性損傷、內(nèi)分泌學(xué)等不同研究領(lǐng)域.開曼生物可提供用于檢測的特色試劑盒,如:類花生酸類物質(zhì)、游離的生物標(biāo)志、環(huán)核苷、激素及氧化氮等;也提供多種高質(zhì)量試劑,包括:類花生酸類物質(zhì)、氧化氮試劑及許多相關(guān)脂質(zhì)、脂肪酸、酶和抗體.作為開曼生物在中國的區(qū)域總代理,艾美捷科技有限公司將為中國客戶提供最全面的開曼生物產(chǎn)品以及客戶訂制化服務(wù).
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