中文名稱

諾西汀（鹽酸鹽）

英文名字

Noscapine (hydrochloride)

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開(kāi)曼生物

產(chǎn)品貨號(hào)

17255-500

產(chǎn)品報(bào)價(jià)

￥1/500mg

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背景資料

Noscapine is an opioid alkaloid with antitussive and antimitotic properties.{28232} It binds to tubulin and arrests mammalian cells in mitosis at a concentration of 20 ?M.{28233} Noscapine induces apoptosis (IC50 = 25 and 10 ?M in HeLa cells and thymocytes, respectively) and demonstrates antitumor activity both in vitro (IC50 = 42.3 and 39.1 ?M in MCF-7 and Renal 1983 cell lines, respectively) and in mice.{28233}

產(chǎn)品描述

An opioid alkaloid that binds to tubulin and arrests mammalian cells in mitosis at a concentration of 20 ?M; induces apoptosis (IC50 = 25 and 10 ?M in HeLa cells and thymocytes, respectively) and demonstrates antitumor activity both in vitro (IC50 = 42.3 and 39.1 ?M) and in mice

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