中文名稱
DFMA | RMI 71897;2-(二氟甲基)精氨酸
英文名字
DFMA|RMI 71897; 2-(difluoromethyl)arginine
供應(yīng)商
開曼生物
產(chǎn)品貨號(hào)
16415-1
產(chǎn)品報(bào)價(jià)
¥415.8/1mg
產(chǎn)品說明書
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購(gòu)買方式
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產(chǎn)品新聞
背景資料
Bacteria synthesize the cellular growth factor putrescine through a number of pathways. One pathway involves the decarboxylation of arginine by arginine decarboxylase to produce agmatine, which is then degraded to putrescine. While important for various cellular processes (e.g., cell division, differentiation, environmental stress responses) in all living organisms, including plants, high levels of this polyamine can be toxic.{23742} α-(difluoromethyl)-DL-Arginine (DFMA) is an enzyme-activated, irreversible inhibitor of the arginine decarboxylases of E. coli (Ki = 800 μM), P. aeruginosa, and K. pneumoniae.{26879} At 0.01 mM, it has been shown to prevent the osmotic stress-induced increase in arginine decarboxylase activity and putrescine synthesis in oat leaf cells.{26875,26878} DFMA can also reduce the growth of T. cruzi in mammalian host cells at a minimal concentration of 10 mM and prevent the growth of C. parvum in a T cell receptor alpha-deficient mouse model when combined with various polyamine analogs.{26877,26876}
產(chǎn)品描述
An enzyme-activated, irreversible inhibitor of the arginine decarboxylases of E. coli (Ki = 800 μM), P. aeruginosa, and K. pneumoniae; prevents the osmotic stress-induced increase in arginine decarboxylase activity and putrescine synthesis in oat leaf cells at 0.01 mM
保存建議
建議您在收到開曼生物品牌的α-(difluoromethyl)-DL-Arginine (1 mg)產(chǎn)品后置于-20度保存,產(chǎn)品有效期為730天.
其他
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