中文名稱

神經(jīng)節(jié)苷脂GQ1b，四鈉鹽

英文名字

Ganglioside GQ1b, tetrasodium salt

供應(yīng)商

開(kāi)曼生物

產(chǎn)品貨號(hào)

15589-500

產(chǎn)品報(bào)價(jià)

￥6847.5/500ug

產(chǎn)品說(shuō)明書(shū)

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產(chǎn)品新聞

背景資料

Gangliosides are formed from a glycosphingolipid combined with one or more sialic acids at the oligosaccharide chain. They are anchored at the outer surface of the plasma membrane where they pack densely with cholesterol to form lipid microdomains that modulate both intra- and inter-cellular signaling events. Ganglioside GQ1b is a tetrasialoganglioside that is characterized by having two sialic residues linked to the inner galactose unit. At 5 nM, it can stimulate an ecto-type (cell-surface) protein phosphorylation system in the human neuroblastoma cell line GOTO.{25486} Ganglioside GQ1b has been reported to promote neurite outgrowth during early neuronal differentiation by activating the ERK1/2 MAP kinase pathway.{25483} It has also been shown to initiate keratinocyte differentiation through phophoinositide turnover.{25487}

產(chǎn)品描述

A tetrasialoganglioside that promotes neurite outgrowth during early neuronal differentiation via ERK1/2 MAP kinase pathway activaton; also initiates keratinocyte differentiation

保存建議

建議您在收到開(kāi)曼生物品牌的Ganglioside GQ1b (sodium salt) (500 μg)產(chǎn)品后置于-20度保存，產(chǎn)品有效期為730天.

其他

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