中文名稱

PicoProbeTM谷氨酰胺酶（GLS）活性測定試劑盒（熒光）

英文名字

PicoProbeTM Glutaminase (GLS) Activity Assay Kit (Fluorometric)

供應(yīng)商

Biovision

產(chǎn)品貨號

K455-100

產(chǎn)品報價

￥8720/100assays

產(chǎn)品說明書

點(diǎn)擊查看

購買方式

銀行轉(zhuǎn)賬、電匯、支票、現(xiàn)金，在線支付寶及網(wǎng)銀支付，或直接與我們電話聯(lián)系400-6800-868.

產(chǎn)品新聞

背景資料

Glutaminase (EC 3.5.1.2) is a mitochondrial enzyme that hydrolyzes glutamine producing glutamate and ammonia. GLS is one of the two key enzymes that are responsible for glutamine homeostasis, the other being glutamine synthetase. Since glutamine is a major metabolic substrate involved in gluconeogenesis, its homeostasis is tightly controlled. Glutaminase has tissue-specific roles in multiple organs, with the isoform GLS1 being expressed in kidneys and brain, and GLS2 being expressed in the liver. It is involved in maintenance of acid-base homeostasis by producing ammonia during renal acidosis in kidneys; and regulation of glutamate –which acts as a neurotransmitter- in the brain. On the other hand, GLS 2 regulates the generation of ammonia in liver by producing urea. Research shows GLS increased activity in individuals facing starvation, diabetes and high protein diets. BioVision’s PicoProbeTM Glutaminase Activity Assay Kit is a simple plate-based fluorometric assay for measuring glutaminase activity in biological samples. GLS hydrolyzes glutamine forming glutamate and ammonia. Glutamate, in the presence of a developer and enzyme mix converts a non-fluorescent probe to a fluorescent product via an enzymatic reaction. The assay can detect as low as 2 μU of glutaminase in biological samples.

產(chǎn)品描述

該產(chǎn)品PicoProbeTM谷氨酰胺酶（GLS）活性測定試劑盒（熒光）又稱PicoProbeTM Glutaminase (GLS) Activity Assay Kit (Fluorometric),是Biovision中國區(qū)域總代理艾美捷科技提供的原裝進(jìn)口產(chǎn)品，具體的產(chǎn)品詳情可查閱產(chǎn)品說明書。

產(chǎn)品特點(diǎn)

Validated with relevant biological samples, Includes human GLS as positive control, Sensitive, specific assay for detection of glutaminase activity in biological samples

保存建議

請在接收到該Biovision品牌的PicoProbeTM谷氨酰胺酶（GLS）活性測定試劑盒（熒光）產(chǎn)品后，將其置于-20°C保存.

其他

BioVision的公司總部在美麗的舊金山灣地區(qū)，它是全球生命科學(xué)公司的Leader，BioVision在開發(fā)和研究細(xì)胞凋亡檢測分析、代謝檢測方面具有卓越的影響力.包括檢測各種檢測分析試劑盒、相關(guān)特色抗體、重組蛋白及細(xì)胞因子和酶等多種產(chǎn)品，以及其他創(chuàng)新的研究工具.其產(chǎn)品覆蓋細(xì)胞凋亡研究、能量代謝、細(xì)胞/組織蛋白提取、氧化應(yīng)激與損傷、代謝與肥胖癥、細(xì)胞增殖與毒性、信號轉(zhuǎn)導(dǎo)、干細(xì)胞研究等領(lǐng)域.作為多家知名品牌的中國總代理以及中國區(qū)域代理，艾美捷與BioVision一起為研究者們提供優(yōu)質(zhì)、新的細(xì)胞生物學(xué)研究工具而不斷擴(kuò)大產(chǎn)品及服務(wù)質(zhì)量.