用途21-羥基-17-(1-氧代丙氧基)孕甾-4-烯-3,20-二酮用作有機合成、醫(yī)藥中間體。生物活性Clascoterone(Winlevi,Cortexolone17alpha-propionate,Cortexolone17α-propionate,CB-03-01)是一種局部的和外周選擇性的androgenreceptor(AR)的拮抗劑。靶點TargetValueAR()體內研究Clascoteroneisanewpotenttopicalantiandrogenpotentiallyusefulinacnevulgaris.Clascoterone1%creamwasverywelltolerated,andwassignificantlybetterthanplaceboregardingTLC(P=0·0017),ILC(P=0·0134)andASI(P=0·0090),andalsoclinicallymoreeffectivethancomparator.Theproductalsoinducedafasterattainmentof50%improvementinalltheaboveparameters.用途信號轉導通路激酶抑制劑