英文名稱：
AZD-0156
CAS號：
1821428-35-6
分子式：
C26H31N5O3
分子量：
461.56
沸點(diǎn)
628.3±55.0 °C(Predicted)
密度
1.242±0.06 g/cm3(Predicted)
酸度系數(shù)(pKa)
9.27±0.28(Predicted)
AZD0156 is an oral, potent and selective ATM kinase inhibitor, inhibiting the kinase activity of ATM and ATM-mediated signaling, preventing DNA damage checkpoint activation, and disrupting DNA damage repair, inducing tumor cell apoptosis, and leading to cell death in ATM-overexpressing tumor cells.
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