Ethidium bromide

別名: Homidium bromide, EtBr, EB 中文名稱：溴化乙啶

目錄號(hào)：S3689 Purity: 99.05%

Ethidium Bromide (Homidium bromide, EtBr, EB) 是一種嵌入劑，與DNA堿基對(duì)類似。EtBr在分子生物學(xué)實(shí)驗(yàn)技術(shù)（如瓊脂糖凝膠電泳）中經(jīng)常被用于熒光標(biāo)記（核酸染色）。

Ethidium bromide Chemical Structure

CAS: 1239-45-8

規(guī)格	價(jià)格	庫(kù)存
25mg	1040.8	現(xiàn)貨
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產(chǎn)品質(zhì)控

批次： S368902 DMSO]79 mg/mL]false]Water]4 mg/mL]false]Ethanol]Insoluble]false 純度： 99.05%

99.05

Ethidium bromide相關(guān)產(chǎn)品

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相關(guān)化合物庫(kù)	FDA藥物庫(kù) 天然產(chǎn)物庫(kù) 已知活性藥物庫(kù)-I 多樣性化合物母核庫(kù)	點(diǎn)擊展開

生物活性

產(chǎn)品描述	Ethidium Bromide (Homidium bromide, EtBr, EB) 是一種嵌入劑，與DNA堿基對(duì)類似。EtBr在分子生物學(xué)實(shí)驗(yàn)技術(shù)（如瓊脂糖凝膠電泳）中經(jīng)常被用于熒光標(biāo)記（核酸染色）。

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
臨床試驗(yàn)信息 (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT06343311	Not yet recruiting	B-Cell Non-Hodgkin''s Lymphoma (NHL)\|Lymphoma Non-Hodgkins\|Lymphomas Non-Hodgkin''s B-Cell\|Non-Hodgkin Lymphoma\|Non-Hodgkin''s Lymphoma\|Large B-Cell Lymphoma\|Lymphoma Non-Hodgkin''s Adult\|Lymphoma\|Refractory Non-Hodgkin Lymphoma\|Relapsed Non-Hodgkin Lymphoma\|Lymphoma Non-Hodgkin\|HIV Associated Lymphoma\|CNS Lymphoma\|High-grade B-cell Lymphoma\|Refractory B-Cell Non-Hodgkin Lymphoma	Estrella Biopharma Inc.\|Eureka Therapeutics Inc.\|Estrella Immunopharma Inc.	May 15 2024	Phase 1\|Phase 2
NCT06073132	Recruiting	Generalized Epidermolysis Bullosa Simplex	TWi Biotechnology Inc.	April 2024	Phase 2\|Phase 3
NCT06378060	Recruiting	Severe Aplastic Anemia	Hematology department of the 920th hospital	March 1 2024	Phase 2
NCT05600140	Recruiting	Vision Disorders\|Vision Low	Royal Dutch Visio\|Radboud University Behavioural Science Institute Nijmegen The Netherlands	March 6 2024	Not Applicable
NCT06007235	Recruiting	Epidermolysis Bullosa Dystrophica\|Epidermolysis Bullosa Junctional	Organ Tissue Regeneration Repair and Replacement\|Euraxi Pharma\|ARANZ Medical	January 29 2024	Not Applicable
NCT05955326	Recruiting	Acute Cerebral Ischemia	Pharmazz Inc.	January 8 2024	Phase 4

參考文獻(xiàn)
[1] Sigmon J, et al. Electrophoresis. 1996, 17(10):1524-7.

參考文獻(xiàn)

[1] Sigmon J, et al. Electrophoresis. 1996, 17(10):1524-7.

化學(xué)信息&溶解度

分子量	394.31	分子式	C₂₁H₂₀N₃.Br
CAS號(hào)	1239-45-8	SDF	Download Ethidium bromide SDF
Smiles	CC[N+]1=C2C=C(C=CC2=C3C=CC(=CC3=C1C4=CC=CC=C4)N)N.[Br-]
儲(chǔ)存條件(自收到貨起)	3年-20°C粉狀	儲(chǔ)備液保存和期限建議分裝儲(chǔ)備液，避免反復(fù)凍融！	1年-80°C溶于溶劑
儲(chǔ)存條件(自收到貨起)	3年-20°C粉狀	儲(chǔ)備液保存和期限建議分裝儲(chǔ)備液，避免反復(fù)凍融！	1個(gè)月-20°C溶于溶劑

體外溶解度
批次：

DMSO : 79 mg/mL ( (200.34 mM) ；DMSO吸濕會(huì)降低化合物溶解度，請(qǐng)使用新開封DMSO)

Water : 4 mg/mL (10.14 mM)

Ethanol : Insoluble

摩爾濃度計(jì)算器

體內(nèi)溶解度
批次：

現(xiàn)配現(xiàn)用，請(qǐng)按從左到右的順序依次添加，澄清后再加入下一溶劑

動(dòng)物體內(nèi)配方計(jì)算器

實(shí)驗(yàn)計(jì)算

摩爾濃度計(jì)算器

質(zhì)量	濃度	體積	分子量
=	×	×

稀釋計(jì)算器分子量計(jì)算器

動(dòng)物體內(nèi)配方計(jì)算器（澄清溶液）

第一步：請(qǐng)輸入基本實(shí)驗(yàn)信息（考慮到實(shí)驗(yàn)過程中的損耗，建議多配一只動(dòng)物的藥量）

給藥劑量 mg/kg 動(dòng)物平均體重 g 每只動(dòng)物給藥體積 μL 動(dòng)物數(shù)量只

第二步：請(qǐng)輸入動(dòng)物體內(nèi)配方組成（配方適用于不溶于水的藥物；不同批次藥物配方比例不同，請(qǐng)聯(lián)系Selleck為您提供正確的澄清溶液配方）

% DMSO + % + % Tween 80 + % ddH2O

%DMSO+ %

計(jì)算結(jié)果：

工作液濃度： mg/ml；

DMSO母液配制方法： mg 藥物溶于μL DMSO溶液（母液濃度mg/mL，注：如該濃度超過該批次藥物DMSO溶解度，請(qǐng)先聯(lián)系Selleck）；

體內(nèi)配方配制方法：取μL DMSO母液，加入μL PEG300，混勻澄清后加入μL Tween 80，混勻澄清后加入μL ddH₂O，混勻澄清。

體內(nèi)配方配制方法：取μL DMSO母液，加入μL Corn oil，混勻澄清。

注意：1. 首先保證母液是澄清的；
2.一定要按照順序依次將溶劑加入，進(jìn)行下一步操作之前必須保證上一步操作得到的是澄清的溶液，可采用渦旋、超聲或水浴加熱等物理方法助溶。

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