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  2. 天然產(chǎn)物
  3. 疾病研究領(lǐng)域 生物堿 微生物
  4. 感染 吡啶類生物堿 吲哚類生物堿
  5. 1-Acetyl-β-carboline

1-Acetyl-β-carboline  (Synonyms: 1-(9H-pyrido[3,4-b]indol-1-yl)ethanone)

目錄號: HY-W060074 純度: 97.04%
COA 產(chǎn)品使用指南 技術(shù)支持

1-Acetyl-β-carboline 是 Nonomuraea endophytica 的代謝產(chǎn)物。

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1-Acetyl-β-carboline Chemical Structure

1-Acetyl-β-carboline Chemical Structure

CAS No. : 50892-83-6

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     可免費申領(lǐng)三個不同產(chǎn)品的試用裝。

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規(guī)格 價格 是否有貨 數(shù)量
1 mg ￥4800
In-stock
5 mg   詢價  
10 mg   詢價  

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  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

1-Acetyl-β-carboline is metabolite of Nonomuraea endophytica[1].

細胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 GI50
> 40 μM
Compound: 41
Cytotoxicity activity against human A549 cells assessed as growth inhibition at 10 ug/ml after 72 hrs sulforhodamine B assay
Cytotoxicity activity against human A549 cells assessed as growth inhibition at 10 ug/ml after 72 hrs sulforhodamine B assay
[PMID: 21316977]
A549 IC50
> 50 μM
Compound: 7
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
[PMID: 21977916]
DU-145 GI50
> 40 μM
Compound: 41
Cytotoxicity activity against human DU145 cells assessed as growth inhibition at 10 ug/ml after 72 hrs sulforhodamine B assay
Cytotoxicity activity against human DU145 cells assessed as growth inhibition at 10 ug/ml after 72 hrs sulforhodamine B assay
[PMID: 21316977]
DU-145 IC50
> 50 μM
Compound: 7
Cytotoxicity against human DU145 cells after 48 hrs by MTT assay
Cytotoxicity against human DU145 cells after 48 hrs by MTT assay
[PMID: 21977916]
HeLa IC50
> 50 μM
Compound: 7
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
[PMID: 21977916]
HT-22 IC50
> 100 μM
Compound: 31
Cytotoxicity against mouse HT-22 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
Cytotoxicity against mouse HT-22 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
[PMID: 36876904]
KB GI50
> 40 μM
Compound: 41
Cytotoxicity activity against human KB cells assessed as growth inhibition at 10 ug/ml after 72 hrs sulforhodamine B assay
Cytotoxicity activity against human KB cells assessed as growth inhibition at 10 ug/ml after 72 hrs sulforhodamine B assay
[PMID: 21316977]
MCF7 IC50
> 50 μM
Compound: 7
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
[PMID: 21977916]
MDA-MB-231 IC50
> 50 μM
Compound: 7
Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay
[PMID: 21977916]
NCI-H460 IC50
> 50 μM
Compound: 7
Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
[PMID: 21977916]
Neutrophil IC50
5.03 μM
Compound: 41
Antiinflammatory activity against human neutrophil assessed as inhibition of N-formyl-l-methionyl phenylalanine/cytochalasin B-induced superoxide anion generation by spectrophotometry
Antiinflammatory activity against human neutrophil assessed as inhibition of N-formyl-l-methionyl phenylalanine/cytochalasin B-induced superoxide anion generation by spectrophotometry
[PMID: 21316977]
SMMC-7721 IC50
> 50 μM
Compound: 7
Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay
Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay
[PMID: 21977916]
SW1990 IC50
> 50 μM
Compound: 7
Cytotoxicity against human SW1990 cells after 48 hrs by MTT assay
Cytotoxicity against human SW1990 cells after 48 hrs by MTT assay
[PMID: 21977916]
分子量

210.23

Formula

C13H10N2O
CAS 號
性狀

固體

顏色

Light yellow to yellow

中文名稱

1-Acetyl一carboline
結(jié)構(gòu)分類
初始來源

Nonomuraea endophytica
運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性數(shù)據(jù)
細胞實驗： 

DMSO 中的溶解度 : 50 mg/mL (237.83 mM; 超聲助溶; 吸濕的 DMSO 對產(chǎn)品的溶解度有顯著影響，請使用新開封的 DMSO)

配制儲備液
濃度 溶劑體積 質(zhì)量 1 mg 5 mg 10 mg
1 mM 4.7567 mL 23.7835 mL 47.5670 mL
5 mM 0.9513 mL 4.7567 mL 9.5134 mL
查看完整儲備液配制表

* 請根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲備液；一旦配成溶液，請分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。
儲備液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C儲存時，請在6個月內(nèi)使用，-20°C儲存時，請在1個月內(nèi)使用。

  • 摩爾計算器

  • 稀釋計算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量
=
濃度
×
體積
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start)

C1

×
體積 (start)

V1

=
濃度 (final)

C2

×
體積 (final)

V2

動物溶解方案計算器
請輸入動物實驗的基本信息：

給藥劑量

mg/kg

動物的平均體重

g

每只動物的給藥體積

μL

動物數(shù)量

只
由于實驗過程有損耗，建議您多配一只動物的量
計算結(jié)果
工作液所需濃度 : mg/mL
純度 & 產(chǎn)品資料
參考文獻

完整儲備液配制表

* 請根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲備液；一旦配成溶液，請分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。
儲備液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C儲存時，請在6個月內(nèi)使用，-20°C儲存時，請在1個月內(nèi)使用。

可選溶劑 濃度 溶劑體積 質(zhì)量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.7567 mL 23.7835 mL 47.5670 mL 118.9174 mL
5 mM 0.9513 mL 4.7567 mL 9.5134 mL 23.7835 mL
10 mM 0.4757 mL 2.3783 mL 4.7567 mL 11.8917 mL
15 mM 0.3171 mL 1.5856 mL 3.1711 mL 7.9278 mL
20 mM 0.2378 mL 1.1892 mL 2.3783 mL 5.9459 mL
25 mM 0.1903 mL 0.9513 mL 1.9027 mL 4.7567 mL
30 mM 0.1586 mL 0.7928 mL 1.5856 mL 3.9639 mL
40 mM 0.1189 mL 0.5946 mL 1.1892 mL 2.9729 mL
50 mM 0.0951 mL 0.4757 mL 0.9513 mL 2.3783 mL
60 mM 0.0793 mL 0.3964 mL 0.7928 mL 1.9820 mL
80 mM 0.0595 mL 0.2973 mL 0.5946 mL 1.4865 mL
100 mM 0.0476 mL 0.2378 mL 0.4757 mL 1.1892 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
1-Acetyl-β-carboline
目錄號：
HY-W060074
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