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  1. Immunology/Inflammation
  2. COX
  3. Apyramide

Apyramide 是一種抗炎試劑 (NSAID),是吲哚美辛 (HY-14397) 的前體。Indomethacin 是一種強效的、血腦通透的、非選擇性的 COX1 和 COX2 抑制劑。

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Apyramide Chemical Structure

Apyramide Chemical Structure

CAS No. : 68483-33-0

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規(guī)格 價格 是否有貨
5 mg ¥2000
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10 mg ¥3400
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20 mg ¥6000
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查看 COX 亞型特異性產(chǎn)品:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

Apyramide is an anti-inflammatory agent (NSAID) and behaves as a proagent of indomethacin (HY-14397). Indomethacin is a potent, blood-brain permeable and nonselective inhibitor of COX1 and COX2.

體內(nèi)研究
(In Vivo)

Apyramide is far less toxic than indomethacin in rats and mice by the oral or the i.p. route. It exhibits anti-inflammatory activity on carrageenin-induced paw oedema, cotton pellet granuloma and adjuvant arthritis, as well as analgesic and antipyretic activities[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

490.93

Formula

C27H23ClN2O5

CAS 號
性狀

固體

顏色

White to off-white

運輸條件

Room temperature in continental US; may vary elsewhere.

儲存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
純度 & 產(chǎn)品資料
參考文獻

Apyramide 相關(guān)分類

  • 摩爾計算器

  • 稀釋計算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱:
Apyramide
目錄號:
HY-U00046
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