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  2. Cytoskeleton
  3. Integrin
  4. α2β1 Integrin Ligand Peptide

α2β1 Integrin Ligand Peptide  (Synonyms: DGEA peptide)

目錄號: HY-P1868
產(chǎn)品使用指南 技術(shù)支持

α2β1 Integrin Ligand Peptide 在細(xì)胞膜表面與 α2β1 整合素受體相互作用,進(jìn)入細(xì)胞介導(dǎo)細(xì)胞外信號。α2β1 Integrin Ligand Peptide是一種潛在的膠原受體拮抗劑。

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Custom Peptide Synthesis

α2β1 Integrin Ligand Peptide Chemical Structure

α2β1 Integrin Ligand Peptide Chemical Structure

CAS No. : 134580-64-6

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3.  試用裝只面向終端客戶。

規(guī)格 是否有貨
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100 mg   詢價  
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α2β1 Integrin Ligand Peptide 的其他形式現(xiàn)貨產(chǎn)品:

Customer Review

Other Forms of α2β1 Integrin Ligand Peptide:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

α2β1 Integrin Ligand Peptide interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors[1].

體外研究
(In Vitro)

α2β1 Integrin Ligand Peptide (DGEA) (0.015-2.0 mM) inhibits SA11, RRV, and Wa infection in a dose-dependent manner and had no effect on CRW-8 infectivity[1].
α2β1 Integrin Ligand Peptide induces tyrosine kinase-dependent calcium mobilization in osteoblasts and fibroblasts at concentrations of ≥0.5 mM[1].
α2β1 Integrin Ligand Peptide loses its ability to inhibit SA11 binding at 1.0 mM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

390.35

Formula

C14H22N4O9
CAS 號
Sequence

Asp-Gly-Glu-Ala
Sequence Shortening

DGEA
運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
細(xì)胞實(shí)驗(yàn)： 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
純度 & 產(chǎn)品資料
參考文獻(xiàn)

  • 摩爾計算器

  • 稀釋計算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
α2β1 Integrin Ligand Peptide
目錄號：
HY-P1868
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