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  2. Autophagy Neuronal Signaling
  3. Autophagy CaMK
  4. Calmodulin-Dependent Protein Kinase II (290-309)

Calmodulin-Dependent Protein Kinase II (290-309) 

目錄號(hào): HY-P1479
產(chǎn)品使用指南

Calmodulin-Dependent Protein Kinase II (290-309) 是有效的 CaMK 拮抗劑， 抑制抑制Ca2+/鈣調(diào)蛋白依賴性蛋白激酶II的 IC50 值為52 nM。

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Custom Peptide Synthesis

Calmodulin-Dependent Protein Kinase II (290-309) Chemical Structure

Calmodulin-Dependent Protein Kinase II (290-309) Chemical Structure

CAS No. : 115044-69-4

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Calmodulin-Dependent Protein Kinase II (290-309) 的其他形式現(xiàn)貨產(chǎn)品:

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Other Forms of Calmodulin-Dependent Protein Kinase II (290-309):

查看 CaMK 亞型特異性產(chǎn)品:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Calmodulin-Dependent Protein Kinase II (290-309) is a potent CaMK antagonist with an IC50 of 52 nM for inhibition of Ca2+/calmodulin-dependent protein kinase II[1].

IC50 & Target

IC50: 52 nM (calmodulin-dependent protein kinase II)[1]
體外研究
(In Vitro)

Peptide 290 to 309 is found to be a potent calmodulin antagonist with an IC50 of 52 nM for inhibition of Ca2+/calmodulin-dependent protein kinase. Neither truncation from the amino terminus (peptide 296-309) nor extension in the carboxyl-terminal direction (peptide 294-319) markedly affects calmodulin binding, whereas shortening the peptide from the carboxyl terminus (peptide 290-302) or from both ends (peptide 295-304) results in the elimination of this activity[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

2273.83

Formula

C103H185N31O24S
CAS 號(hào)
Sequence

Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala
Sequence Shortening

LKKFNARRKLKGAILTTMLA
運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.
儲(chǔ)存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
純度 & 產(chǎn)品資料
參考文獻(xiàn)

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
Calmodulin-Dependent Protein Kinase II (290-309)
目錄號(hào)：
HY-P1479
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